Annotation Detail
Information
- Associated Genes
- KMT2A
- Associated Variants
-
KMT2A MUTATION
KMT2A MUTATION - Associated Disease
- Leukemogenesis
- Source Database
- DisGeNET
- Description
- This review focuses on the molecular mechanisms underlying MLL1 translocation-driven leukemogenesis and the latest progress on DOT1L-targeted epigenetic therapies for MLL1-rearranged and other leukemias.
- Pubmed
- 26118503
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 9
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0228011172547455
Drugs