Annotation Detail

Information
Associated Genes
STAT5B
Associated Variants
STAT5B MUTATION
STAT5B MUTATION
Associated Disease
Leukemogenesis
Source Database
DisGeNET
Description
These results reveal a leukemic pathway involving FAK/Tiam1/Rac1/PAK1 and demonstrate an essential role for these signaling molecules in regulating the nuclear translocation of Stat5 in leukemogenesis.
Pubmed
25456130
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00434306995328485
Drugs