Annotation Detail
Information
- Associated Genes
- BDNF
- Associated Variants
-
BDNF MUTATION
BDNF MUTATION - Associated Disease
- depressive disorder
- Source Database
- DisGeNET
- Description
- A brain-derived neurotrophic factor (BDNF) prodomain single-nucleotide polymorphism resulting in a valine to methionine substitution (Val66Met) has been associated with depression-related phenotypes and brain alterations involving regions consistently associated with major depressive disorder (MDD).
- Pubmed
- 23165919
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.248326584751958
- Year of publication
- 2013
Drugs