Annotation Detail

Information
Associated Genes
PIK3CB
Associated Variants
PIK3CB MUTATION
PIK3CB MUTATION
Associated Disease
Carcinogenesis
Source Database
DisGeNET
Description
Our findings support the de-regulation of the PI3K/Akt/mTOR and MAPK signaling pathways in type I endometrial carcinomas suggesting involvement of these pivotal pathways in endometrial carcinogenesis.
Pubmed
25862896
Section of the abstract supporting the evidence
CONCLUSION
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0347445596262788
Drugs