Annotation Detail

Information
Associated Genes
TNFSF10
Associated Variants
TNFSF10 MUTATION
TNFSF10 MUTATION
Associated Disease
Carcinogenesis
Source Database
DisGeNET
Description
Enforced expression of miR-148a sensitized cells to TRAIL and reduced lung tumorigenesis in vitro and in vivo through the down-modulation of matrix metalloproteinase 15 (MMP15) and Rho-associated kinase 1 (ROCK1).
Pubmed
26124099
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00325730246496364
Drugs