Annotation Detail

Information
Associated Genes
CDH1
Associated Variants
CDH1 MUTATION
CDH1 MUTATION
Associated Disease
Carcinogenesis
Source Database
DisGeNET
Description
To investigate if the coordinated loss of Cdh1 and Tgfbr2 is sufficient to induce tumorigenesis in vivo, we developed two mouse models targeting ablation of both genes constitutively or inducibly in the oral-esophageal epithelium.
Pubmed
25233932
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0130292098598546
Drugs