Annotation Detail
Information
- Associated Genes
- CDH1
- Associated Variants
-
CDH1 MUTATION
CDH1 MUTATION - Associated Disease
- Carcinogenesis
- Source Database
- DisGeNET
- Description
- Further, Cdh1(d/d)Trp53(d/d) tumors in 12-month-old mice were highly aggressive, and metastasized to nearby and distant organs within the peritoneal cavity, such as abdominal lymph nodes, mesentery and peri-intestinal adipose tissues, demonstrating that tumorigenesis in this model proceeds through the universally recognized morphological intermediates associated with type II endometrial neoplasia.
- Pubmed
- 24998851
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0130292098598546
Drugs