Annotation Detail

Information
Associated Genes
CASP8
Associated Variants
CASP8 MUTATION
CASP8 MUTATION
Associated Disease
Carcinogenesis
Source Database
DisGeNET
Description
The signals of carcinogenesis modulate the central control points of the apoptotic pathways, including inhibitor of apoptosis (IAP) proteins and FLICE-inhibitory protein (c-FLIP).
Pubmed
25013758
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00298586059288334
Drugs