Annotation Detail

Information
Associated Genes
GCG
Associated Variants
GCG MUTATION
GCG MUTATION
KCNJ11 p.Lys23Glu (p.K23E) ( ENST00000528731.1, ENST00000339994.5, ENST00000682350.1, ENST00000682764.1 )
KCNJ11 p.Lys23Glu (p.K23E) ( ENST00000339994.5, ENST00000528731.1, ENST00000682350.1, ENST00000682764.1 )
Associated Disease
hyperglycemia
Source Database
DisGeNET
Description
The prevalent Glu23Lys polymorphism in the potassium inward rectifier 6.2 (KIR6.2) gene is associated with impaired glucagon suppression in response to hyperglycemia.
Pubmed
12196481
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.126786046802008
Year of publication
2002
Drugs