Annotation Detail
Information
- Associated Genes
- SERPINE1
- Associated Variants
-
SERPINE1 MUTATION
SERPINE1 MUTATION - Associated Disease
- Factor V Leiden mutation
- Source Database
- DisGeNET
- Description
- In terms of subgroup analyses on co-existence of other thrombotic risk factors, the PAI-1 4G/5G polymorphism was significantly associated with VTE risk in patients with factor V Leiden mutation (dominant model: OR=1.72, 95%CI: 1.17-2.53), but not in patients with cancer or surgery.
- Pubmed
- 25450536
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 10
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00434306995328485
Drugs