Annotation Detail
Information
- Associated Genes
- GLO1
- Associated Variants
-
GLO1 MUTATION
GLO1 MUTATION
GLO1 p.Glu111Ala (p.E111A) ( ENST00000373365.5 )
GLO1 p.Glu111Ala (p.E111A) ( ENST00000373365.5 ) - Associated Disease
- diabetes mellitus
- Source Database
- DisGeNET
- Description
- In a multiple regression analysis with GLO1 activity as the dependent variable, including the Ala111Glu polymorphism, the significant independent variables were log GSSG (ß - 0.318, p = 0.02) and HbA1c (ß 0.285, p = 0.041) in the diabetes group and log GSH, (ß 0.407, p = 0.004) in the control group.
- Pubmed
- 23360186
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00352874433704394
- Year of publication
- 2013
Drugs