Annotation Detail

Information
Associated Genes
CASP8
Associated Variants
CASP8 MUTATION
CASP8 MUTATION
Associated Disease
Ewings sarcoma
Source Database
DisGeNET
Description
Gene modified MSC expressing TRAIL were cocultured with different osteosarcoma, rhabdomyosarcoma, and Ewing's Sarcoma (ES) cell lines assessing viability and caspase-8 activation.
Pubmed
25420617
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs