Annotation Detail

Information
Associated Genes
PIK3CB
Associated Variants
PIK3CB MUTATION
PIK3CB MUTATION
Associated Disease
Thyroid carcinoma
Source Database
DisGeNET
Description
The present review focuses on the most recent developments on the role of the PI3K/Akt pathway in the pathogenesis of non-medullary TC and will provide insight into how this pathway can be targeted either alone or in the context of multimodal therapeutic strategies for treatment of advanced TC.
Pubmed
26138515
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00651460492992728
Drugs