Annotation Detail
Information
- Associated Genes
- CTLA4
- Associated Variants
-
RSBN1 p.Arg31= (p.R31=)
(
ENST00000612242.4,
ENST00000261441.9 )
RSBN1 p.Arg31= (p.R31=) ( ENST00000612242.4, ENST00000261441.9 )
rs7528684
RSBN1 p.Arg31= (p.R31=) ( ENST00000261441.9, ENST00000612242.4 )
RSBN1 p.Arg31= (p.R31=) ( ENST00000261441.9, ENST00000612242.4 )
rs7528684 - Associated Disease
- Graves Disease
- Source Database
- DisGeNET
- Description
- These preliminary results demonstrate that the immune-regulatory gene CTLA-4 and the thyroid-specific gene Tg contribute to the risk of Graves' disease with additive effects, while PTPN22 rs3789604 and FCRL3 rs7528684 polymorphisms are protective against the disease.
- Pubmed
- 19438904
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.228259749261344
- Year of publication
- 2010
Drugs