Annotation Detail
Information
- Associated Genes
- IL23R
- Associated Variants
-
IL23R p.His161Arg (p.H161R)
(
ENST00000347310.10,
ENST00000697154.1,
ENST00000371007.6,
ENST00000697165.1,
ENST00000697164.1,
ENST00000697230.1,
ENST00000697163.1 )
IL17F p.His161Arg (p.H161R) ( ENST00000336123.5, ENST00000699946.1 )
IL23R p.His161Arg (p.H161R) ( ENST00000347310.10, ENST00000697154.1, ENST00000697163.1, ENST00000697164.1, ENST00000697165.1, ENST00000697230.1, ENST00000371007.6 )
IL17F p.His161Arg (p.H161R) ( ENST00000336123.5, ENST00000699946.1 ) - Associated Disease
- ulcerative colitis
- Source Database
- DisGeNET
- Description
- Given the association of IL23R with inflammatory bowel disease (IBD), we characterized the role of IL-17F in IBD including its intestinal gene expression and the effect of the IL17F p.His161Arg polymorphism on disease susceptibility and phenotype of Crohn's disease (CD) and ulcerative colitis (UC).
- Pubmed
- 18088064
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.326936272243952
- Year of publication
- 2008
Drugs