Annotation Detail

Information
Associated Genes
GEMIN4
Associated Variants
GEMIN4 p.Arg1033Cys (p.R1033C) ( ENST00000576778.1, ENST00000319004.6 )
AGO1 c.1020+2605G>A ( ENST00000373204.6, ENST00000373206.5, ENST00000674426.1 )
DGCR8 c.*1700G>A ( ENST00000351989.8, ENST00000407755.2, ENST00000704820.1, ENST00000704821.1 )
GEMIN4 p.Arg1033Cys (p.R1033C) ( ENST00000319004.6, ENST00000576778.1 )
AGO1 c.1020+2605G>A ( ENST00000373204.6, ENST00000373206.5, ENST00000674426.1 )
DGCR8 c.*1700G>A ( ENST00000351989.8, ENST00000407755.2, ENST00000704820.1, ENST00000704821.1 )
Associated Disease
Hepatitis B, Chronic
Source Database
DisGeNET
Description
To explore the relationship between three SNPs (rs3757 in DGCR8, rs636832 in AGO1, rs7813 in GEMIN4) in miRNA-machinery genes and chronic hepatitis B, we genotyped the SNPs by high resolution melting method (HRM) in a case-control study of 332 unrelated chronic hepatitis B patients and 352 unrelated healthy controls in Western China.
Pubmed
25239527
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2014
Drugs