Annotation Detail
Information
- Associated Genes
- TP53
- Associated Variants
-
TP53 MUTATION
TP53 MUTATION
rs3829787
CHRNA5 c.106+7258T>C ( ENST00000299565.9, ENST00000559554.5 )
CHRNA3 c.268-64C>A ( ENST00000348639.7, ENST00000326828.6 )
rs3829787
CHRNA5 c.106+7258T>C ( ENST00000299565.9, ENST00000559554.5 )
CHRNA3 c.268-64C>A ( ENST00000326828.6, ENST00000348639.7 ) - Associated Disease
- Lung Neoplasms
- Source Database
- DisGeNET
- Description
- We found that four of the variants (rs3829787, rs3841324, rs588765 and rs3743073) were associated with differential levels of genetic alterations measured as the levels of hydrophobic DNA adducts in the adjacent histologically normal tissue of the lung cancer patients and as TP53 mutations in their lung tumors.
- Pubmed
- 23011884
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.326818823782967
- Year of publication
- 2013
Drugs