Annotation Detail

Information
Associated Genes
SOCS1
Associated Variants
SOCS1 MUTATION
SOCS1 MUTATION
Associated Disease
Hematologic Neoplasms
Source Database
DisGeNET
Description
The inactivation of suppressor of cytokine signaling SOCS-1, a negative regulator of cytokine pathways, by hypermethylation was shown in hematological malignancies including Myelsplastic Syndromes.
Pubmed
25123164
Section of the abstract supporting the evidence
INTRODUCTION
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs