Annotation Detail
Information
- Associated Genes
- IL23R
- Associated Variants
-
TLR9 p.Pro545= (p.P545=)
(
ENST00000360658.3 )
TLR9 p.Pro545= (p.P545=) ( ENST00000360658.3 )
rs5743836
TLR9 p.Pro545= (p.P545=) ( ENST00000360658.3 )
TLR9 p.Pro545= (p.P545=) ( ENST00000360658.3 )
rs5743836 - Associated Disease
- Inflammatory Bowel Diseases
- Source Database
- DisGeNET
- Description
- The single-nucleotide polymorphisms (SNPs) -1237T/C (rs5743836) and 2848A/G (rs352140=p.Pro545Pro) in TLR9, the main CD-associated variants within the genes for NOD2, IL23R, ATG16L1, and variants in the IBD5 locus and in the DLG5 gene were assessed in 956 patients with IBD (606 CD and 350 ulcerative colitis) and in 792 healthy controls.
- Pubmed
- 19455129
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.340104897278974
- Year of publication
- 2009
Drugs