Annotation Detail

Information
Associated Genes
LRRK2
Associated Variants
LRRK2 p.Gly2019Ser (p.G2019S) ( ENST00000298910.12, ENST00000680790.1 )
LRRK2 p.Gly2019Ser (p.G2019S) ( ENST00000298910.12, ENST00000680790.1 )
Associated Disease
Parkinsonian Disorders
Source Database
DisGeNET
Description
A series of 106 patients with isolated or familial Parkinsonism underwent clinical evaluation and genetic testing for the LRRK2 G2019S mutation which was identified in 34/106 patients (32%).
Pubmed
20933457
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.159157150231213
Year of publication
2010
Drugs