Annotation Detail

Information
Associated Genes
IL1B
Associated Variants
IL1B MUTATION
IL1B MUTATION
Associated Disease
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
Source Database
DisGeNET
Description
Inflammasome activation and caspase-1-dependent (CASP1-dependent) processing and secretion of IL-1β and IL-18 are critical events at the interface of the bacterial pathogen Helicobacter pylori with its host.
Pubmed
26214524
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0100433492669712
Drugs