Annotation Detail

Information
Associated Genes
LRRK2
Associated Variants
LRRK2 p.Ile2012Thr (p.I2012T) ( ENST00000298910.12, ENST00000680790.1 )
LRRK2 p.Gly2019Ser (p.G2019S) ( ENST00000298910.12, ENST00000680790.1 )
LRRK2 p.Ile2020Thr (p.I2020T) ( ENST00000298910.12, ENST00000680790.1 )
LRRK2 p.Ile2012Thr (p.I2012T) ( ENST00000298910.12, ENST00000680790.1 )
LRRK2 p.Gly2019Ser (p.G2019S) ( ENST00000298910.12, ENST00000680790.1 )
LRRK2 p.Ile2020Thr (p.I2020T) ( ENST00000298910.12, ENST00000680790.1 )
Associated Disease
essential tremor
Source Database
DisGeNET
Description
The LRRK2 I2012T, G2019S and I2020T mutations are not common in patients with essential tremor.
Pubmed
16939701
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00854418168799245
Year of publication
2006
Drugs