Annotation Detail

Information
Associated Genes
IDH2
Associated Variants
IDH2 MUTATION
IDH2 MUTATION
Associated Disease
intrahepatic cholangiocarcinoma
Source Database
DisGeNET
Description
In line with these findings, human ICC with IDH mutations are characterized by a hepatic progenitor cell transcriptional signature suggesting that they are a distinct ICC subtype as compared to IDH wild type tumors.
Pubmed
25485496
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Drugs