Annotation Detail
Information
- Associated Genes
- IL1RN
- Associated Variants
-
IL1RN p.Ser133Arg (p.S133R)
(
ENST00000259206.9,
ENST00000354115.6,
ENST00000361779.7,
ENST00000409930.4,
ENST00000696879.1,
ENST00000696881.1 )
IL1RN p.Ser133= (p.S133=) ( ENST00000259206.9, ENST00000354115.6, ENST00000361779.7, ENST00000409930.4, ENST00000696879.1, ENST00000696881.1 )
IL1RN p.Ser133Arg (p.S133R) ( ENST00000259206.9, ENST00000354115.6, ENST00000361779.7, ENST00000409930.4, ENST00000696879.1, ENST00000696881.1 )
IL1RN p.Ser133= (p.S133=) ( ENST00000259206.9, ENST00000354115.6, ENST00000361779.7, ENST00000409930.4, ENST00000696879.1, ENST00000696881.1 ) - Associated Disease
- Respiratory Distress Syndrome, Adult
- Source Database
- DisGeNET
- Description
- We hypothesized that a synonymous coding variant in the IL-1 receptor antagonist gene (IL1RN), rs315952, previously associated with reduced risk for acute respiratory distress syndrome, would be functional and associate with improved survival in septic shock.
- Pubmed
- 25089931
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0831813575948429
- Year of publication
- 2014
Drugs