Annotation Detail
Information
- Associated Genes
- HLA-DPB1
- Associated Variants
-
rs9267665
(
ENST00000452323.7,
ENST00000469372.5,
ENST00000497706.6,
ENST00000695637.1 )
rs3135363
HLA-DPB1 c.*550A>G ( ENST00000416804.2, ENST00000428835.6, ENST00000418931.7 )
rs9267665 ( ENST00000452323.7, ENST00000469372.5, ENST00000497706.6, ENST00000695637.1 )
rs3135363
HLA-DPB1 c.*550A>G ( ENST00000416804.2, ENST00000418931.7, ENST00000428835.6 ) - Associated Disease
- Hepatitis B, Chronic
- Source Database
- DisGeNET
- Description
- These appear to implicate HLA-DR [rs3135363; P= 6.53 × 10(-22); odds ratio (OR) = 1.53, 95% confidence interval (CI) = 1.35-1.74]; HLA-DP, previously associated with the risk of chronic hepatitis B infection (rs9277535; P= 2.91 × 10(-12); OR = 0.72, 95% CI = 0.63-0.81); and a gene rich HLA Class III interval (rs9267665; P = 1.24 × 10(-17); OR = 2.05, CI = 1.64-2.57).
- Pubmed
- 21764829
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.25090128214493
- Year of publication
- 2011
Drugs