Annotation Detail
Information
- Associated Genes
- LEP
- Associated Variants
-
LEPR p.Gln223Arg (p.Q223R)
(
ENST00000344610.12,
ENST00000371058.1,
ENST00000371060.7,
ENST00000616738.4,
ENST00000371059.7,
ENST00000349533.11 )
POMC c.-51+266C>G ( ENST00000264708.7, ENST00000380794.5, ENST00000395826.7, ENST00000405623.5 )
rs3754860
rs7799039
LEPR p.Gln223Arg (p.Q223R) ( ENST00000344610.12, ENST00000349533.11, ENST00000371058.1, ENST00000371059.7, ENST00000371060.7, ENST00000616738.4 )
POMC c.-51+266C>G ( ENST00000264708.7, ENST00000380794.5, ENST00000395826.7, ENST00000405623.5 )
rs3754860
rs7799039 - Associated Disease
- congestive heart failure
- Source Database
- DisGeNET
- Description
- The aim of this study was to investigate the possible associations of defined variability in leptin (dbSNP ID rs7799039), proopiomelanocortin (dbSNP ID rs3754860 and dbSNP ID rs1009388), and leptin receptor gene (dbSNP rs1137101) with CHF and evaluate their potential as the CHF susceptibility genes.
- Pubmed
- 19337797
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00108576748832121
- Year of publication
- 2009
Drugs