Annotation Detail
Information
- Associated Genes
- HLA-DPA1
- Associated Variants
-
HLA-DPA1 c.*115T>C
(
ENST00000419277.5,
ENST00000692443.1 )
HLA-DPB1 c.*936T>C ( ENST00000428835.6, ENST00000418931.7 )
HLA-DPA1 c.*115T>C ( ENST00000419277.5, ENST00000692443.1 )
HLA-DPB1 c.*936T>C ( ENST00000418931.7, ENST00000428835.6 ) - Associated Disease
- Hepatitis B, Chronic
- Source Database
- DisGeNET
- Description
- We also found that the HLA-DPA1 and HLA-DPB1 genes were significantly associated with protective effects against chronic hepatitis B (CHB) in Japanese, Korean and other Asian populations, including Chinese and Thai individuals (P(meta) = 4.40×10⁻¹⁹ for rs3077 and P(meta) = 1.28×10⁻¹⁵ for rs9277542).
- Pubmed
- 22737229
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.248186863424127
- Year of publication
- 2012
Drugs