Annotation Detail
Information
- Associated Genes
- GCNT2
- Associated Variants
-
HLA-DPA1 c.*115T>C
(
ENST00000419277.5,
ENST00000692443.1 )
HLA-DPB1 c.*550A>G ( ENST00000416804.2, ENST00000428835.6, ENST00000418931.7 )
HLA-DPA1 c.*115T>C ( ENST00000419277.5, ENST00000692443.1 )
HLA-DPB1 c.*550A>G ( ENST00000416804.2, ENST00000418931.7, ENST00000428835.6 ) - Associated Disease
- Hepatitis B, Chronic
- Source Database
- DisGeNET
- Description
- A genome-wide association study identified single nucleotide polymorphisms (SNPs) rs3077 and rs9277535 located in the 3' untranslated regions of human leukocyte antigen (HLA) class II genes HLA-DPA1 and HLA-DPB1, respectively, as the independent variants most strongly associated with chronic hepatitis B.
- Pubmed
- 21346778
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00108576748832121
- Year of publication
- 2011
Drugs