Annotation Detail
Information
- Associated Genes
- APOE
- Associated Variants
-
APOE MUTATION
APOE MUTATION - Associated Disease
- Impaired cognition
- Source Database
- DisGeNET
- Description
- The ε4 allele of apolipoprotein E (APOE ε4) is a well-established risk factor for Alzheimer's disease (AD), and may confer anatomic and functional effects years before clinical signs of cognitive decline are observed.
- Pubmed
- 25738563
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree,GAD,GWASCAT
- DisGENET score for the Gene Disease association
- 0.199576075781247
Drugs