Annotation Detail

Information
Associated Genes
APOE
Associated Variants
APOE MUTATION
APOE MUTATION
Associated Disease
Impaired cognition
Source Database
DisGeNET
Description
Moreover, the interaction of APOE by age on brain morphology may accelerate the pathological progression of late-life cognitive decline in aMCI with ε4-carriers and delay the possible conversion from aMCI with ε2-carriers to AD.
Pubmed
25114090
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree,GAD,GWASCAT
DisGENET score for the Gene Disease association
0.199576075781247
Drugs