Annotation Detail

Information
Associated Genes
APOE
Associated Variants
APOE MUTATION
APOE MUTATION
Associated Disease
Impaired cognition
Source Database
DisGeNET
Description
Deploying a between-sibling design that allows quasi-experimental variation in genotype and educational attainment within a standard gene-environment interaction framework, we show evidence that the genetic effects of the risky APOE variant on old-age cognitive decline are absent in individuals who complete college (vs. high school graduates).
Pubmed
25074513
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree,GAD,GWASCAT
DisGENET score for the Gene Disease association
0.199576075781247
Drugs