Annotation Detail
Information
- Associated Genes
- APOE
- Associated Variants
-
APOE MUTATION
APOE MUTATION - Associated Disease
- Impaired cognition
- Source Database
- DisGeNET
- Description
- Hypertension moderated the effects of APOE ε4 on the rate of change for cognitive flexibility, such that the presence of the APOE ε4 allele and hypertension was associated with steeper cognitive decline over a 21-year period.
- Pubmed
- 24956008
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree,GAD,GWASCAT
- DisGENET score for the Gene Disease association
- 0.199576075781247
Drugs