Annotation Detail

Information
Associated Genes
F2R
Associated Variants
F2R MUTATION
F2R MUTATION
Associated Disease
Adenocarcinoma of colon
Source Database
DisGeNET
Description
Collectively, our findings established a functional role for thrombin and its targets PAR-1 and fibrinogen in the pathogenesis of colonic adenocarcinoma, supporting tumor growth as well as local invasion and metastasis.
Pubmed
26238780
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs