Annotation Detail

Information
Associated Genes
CDKN2A
Associated Variants
CDKN2A MUTATION
CDKN2A MUTATION
Associated Disease
anaplastic oligodendroglioma
Source Database
DisGeNET
Description
Within the 1p/19q-codeleted AO, the contrast enhancement was associated with larger tumor volumes (P = .001), chromosome 9p loss and CDKN2A loss (P = .006), genomic instability (P = .03), and angiogenesis-related gene expression (P < .001), particularly for vascular endothelial growth factor A and angiopoietin 2.
Pubmed
24353325
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00352874433704394
Drugs