Annotation Detail
Information
- Associated Genes
- TCF7L2
- Associated Variants
-
TCF7L2 MUTATION
TCF7L2 MUTATION
TCF7L2 c.876-1026C>T ( ENST00000538897.5, ENST00000352065.10, ENST00000369397.8, ENST00000369389.7, ENST00000355995.9, ENST00000534894.5, ENST00000277945.12, ENST00000369395.6, ENST00000355717.9, ENST00000545257.6, ENST00000629706.2, ENST00000349937.8, ENST00000704420.1, ENST00000627217.3, ENST00000704414.1 )
KCNJ11 p.Lys23Glu (p.K23E) ( ENST00000528731.1, ENST00000339994.5, ENST00000682350.1, ENST00000682764.1 )
TCF7L2 c.876-1026C>T ( ENST00000277945.12, ENST00000349937.8, ENST00000352065.10, ENST00000355717.9, ENST00000355995.9, ENST00000369389.7, ENST00000369395.6, ENST00000369397.8, ENST00000534894.5, ENST00000538897.5, ENST00000545257.6, ENST00000627217.3, ENST00000629706.2, ENST00000704414.1, ENST00000704420.1 )
KCNJ11 p.Lys23Glu (p.K23E) ( ENST00000339994.5, ENST00000528731.1, ENST00000682350.1, ENST00000682764.1 ) - Associated Disease
- Diabetes Mellitus, Non-Insulin-Dependent
- Source Database
- DisGeNET
- Description
- KCNJ11 Lys23Glu and TCF7L2 rs290487(C/T) polymorphisms affect therapeutic efficacy of repaglinide in Chinese patients with type 2 diabetes.
- Pubmed
- 20054294
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.613988408391434
- Year of publication
- 2010
Drugs