Annotation Detail

Information
Associated Genes
PIK3CA
Associated Variants
PIK3CA MUTATION
PIK3CA MUTATION
Associated Disease
Squamous cell carcinoma of oropharynx
Source Database
DisGeNET
Description
PIK3CA mutations are more common in HPV(+) OPSCC and are associated with activation of mTOR, but not AKT.
Pubmed
24599934
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
15
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs