Annotation Detail

Information
Associated Genes
TLR3
Associated Variants
TLR3 MUTATION
TLR3 MUTATION
Associated Disease
Herpes encephalitis
Source Database
DisGeNET
Description
Herpes simplex encephalitis (HSE) in children has previously been linked to defects in type I interferon (IFN) production downstream of Toll-like receptor 3.
Pubmed
26216125
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,CTD_human
DisGENET score for the Gene Disease association
0.123528744337044
Drugs