Annotation Detail

Information
Associated Genes
PGR
Associated Variants
PGR MUTATION
PGR MUTATION
Associated Disease
Impaired glucose tolerance
Source Database
DisGeNET
Description
This phenomenon is regulated through an interaction between SMTNL1 and progesterone receptor, which alters the expression of contractile and metabolic proteins. smtnl1(-/-) mice are metabolically less efficient and show impaired glucose tolerance.
Pubmed
26048986
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs