Annotation Detail
Information
- Associated Genes
- F2R
- Associated Variants
-
F2R MUTATION
F2R MUTATION - Associated Disease
- Sepsis
- Source Database
- DisGeNET
- Description
- The cytoprotective effects are protease activated receptor 1 (PAR-1) and endothelial protein C receptor (EPCR) dependent and likely underlie protective effects of APC in animal models of sepsis, myocardial infarction and ischemic stroke.
- Pubmed
- 25032959
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree,LHGDN
- DisGENET score for the Gene Disease association
- 0.00353867585870808
Drugs