Annotation Detail
Information
- Associated Genes
- F2R
- Associated Variants
-
F2R MUTATION
F2R MUTATION - Associated Disease
- Proliferative vitreoretinopathy
- Source Database
- DisGeNET
- Description
- The purpose of this study was to identify interacting signaling pathways by which the activation of PAR1 by thrombin triggers cyclin D1 gene (Ccnd1) expression and the proliferation of RPE cells, characteristic of proliferative vitreoretinopathy (PVR).
- Pubmed
- 26247679
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs