Annotation Detail
Information
- Associated Genes
- ABCG2
- Associated Variants
-
ABCG2 MUTATION
ABCG2 MUTATION - Associated Disease
- Malignant neoplasm of lung
- Source Database
- DisGeNET
- Description
- We further found that the PI3K/Akt inhibitor LY294002 down-regulated BCRP expression, hence showing that the Akt pathway is involved in the regulation of BCRP expression but not in its localization in these lung cancer cell lines.
- Pubmed
- 25479544
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.0117156077611713
Drugs