Annotation Detail

Information
Associated Genes
IL6
Associated Variants
CD14 c.-221-39T>C ( ENST00000498971.7, ENST00000512545.2, ENST00000519715.2 )
CD14 c.-221-39T>C ( ENST00000498971.7, ENST00000512545.2, ENST00000519715.2 )
Associated Disease
carotid stenosis
Source Database
DisGeNET
Description
To better clarify the role of CD14 in atherosclerosis, we typed CD14 C-260T polymorphism in old Italian (Central of Italy) atherosclerotic patients with carotid stenosis related to lipid assessment, inflammation (soluble CD14, IL-6 serum levels) and IL-6, TNF-alpha, IL-10, Metallothioneins (MT) gene expressions in carotid plaques.
Pubmed
17098305
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00299579211454747
Year of publication
2007
Drugs