Annotation Detail
Information
- Associated Genes
- SLC6A4
- Associated Variants
-
rs25531
rs25531 - Associated Disease
- Unipolar Depression
- Source Database
- DisGeNET
- Description
- A variable number of tandem repeats (short (S) vs long (L)) in the promoter region of the serotonin transporter gene (5-HTTLPR) and a functional variant of a single-nucleotide polymorphism (rs25531) in 5-HTTLPR have been recently associated with increased risk for major depressive disorder (MDD).
- Pubmed
- 20090673
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0381214142230814
- Year of publication
- 2010
Drugs