Annotation Detail
Information
- Associated Genes
- SLC6A4
- Associated Variants
-
rs25531
rs25531 - Associated Disease
- Unipolar Depression
- Source Database
- DisGeNET
- Description
- Utilizing a triallelic assay (5-HTTLPR and rs25531) to assess genetic variation linked with altered serotonin signaling, this fMRI study investigated genetic influences on amygdala and anterior insula activity in 50 generalized anxiety disorder patients, 26 of whom also met DSM-IV criteria for social anxiety disorder and/or major depressive disorder, and 39 healthy comparison subjects.
- Pubmed
- 25675343
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0381214142230814
- Year of publication
- 2014
Drugs