Annotation Detail

Information
Associated Genes
TPH2
Associated Variants
TPH2 p.Pro312= (p.P312=) ( ENST00000333850.4 )
rs25531
TPH2 p.Pro312= (p.P312=) ( ENST00000333850.4 )
rs25531
Associated Disease
depressive disorder
Source Database
DisGeNET
Description
We hypothesize that functional polymorphisms (TPH2: rs7305115, 5-HTTLPR and rs25531) within both genes contribute to the risk of depressive disorders after childhood abuse in adult life.
Pubmed
25214390
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.126514604929927
Year of publication
2014
Drugs