Annotation Detail

Information
Associated Genes
XRCC1
Associated Variants
XRCC1 MUTATION
XRCC1 MUTATION
XRCC1 p.Gln399Arg (p.Q399R) ( ENST00000262887.10, ENST00000543982.5 )
XRCC1 p.Gln399Arg (p.Q399R) ( ENST00000262887.10, ENST00000543982.5 )
Associated Disease
Non-small cell lung carcinoma
Source Database
DisGeNET
Description
Genetic polymorphism of XRCC1 Arg399Gln is associated with survival in non-small-cell lung cancer patients treated with gemcitabine/platinum.
Pubmed
22551904
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0124103812455733
Year of publication
2012
Drugs