Annotation Detail
Information
- Associated Genes
- IFNL3
- Associated Variants
-
IFNL3 MUTATION
IFNL3 MUTATION - Associated Disease
- Fibrosis, Liver
- Source Database
- DisGeNET
- Description
- Interestingly, in the subset of patients with baseline advanced liver fibrosis (Metavir F3-F4), those with treatment failure experienced less hepatic decompensation events or deaths than untreated patients (19% versus 42%; P=0.005) and this finding was more pronounced in patients harbouring IL28B-CC alleles (15.8% versus 47.4%; P=0.02).
- Pubmed
- 25105286
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 9
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00760037241824849
Drugs