Annotation Detail

Information
Associated Genes
IFNL3
Associated Variants
IFNL3 MUTATION
IFNL3 MUTATION
Associated Disease
Fibrosis, Liver
Source Database
DisGeNET
Description
To perform a comprehensive study on independent modulators of liver fibrosis progression and determinants of portal pressure considering immune status, insulin resistance (IR), serum 25-hydroxyvitamin D (25(OH)D) levels, genetic variants of patatin-like phospholipase domain-containing protein 3 (PNPLA3) and interleukin 28B (IL28B) in a thoroughly documented cohort of HIV/hepatitis C-coinfected (HIV/HCV) patients.
Pubmed
24905495
Section of the abstract supporting the evidence
BACKGROUND & AIMS
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00760037241824849
Drugs