Annotation Detail

Information
Associated Genes
XRCC1
Associated Variants
XRCC1 MUTATION
XRCC1 MUTATION
XRCC1 p.Gln399Arg (p.Q399R) ( ENST00000262887.10, ENST00000543982.5 )
XRCC1 p.Gln399Arg (p.Q399R) ( ENST00000262887.10, ENST00000543982.5 )
Associated Disease
Non-small cell lung carcinoma
Source Database
DisGeNET
Description
This study confirms the prognostic role of ERCC1 expression and XRCC1 (Arg399Gln) polymorphism in advanced NSCLC treated with first-line chemotherapy.
Pubmed
23549037
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0124103812455733
Year of publication
2013
Drugs