Annotation Detail

Information
Associated Genes
PCLO
Associated Variants
PCLO p.Ser4814Ala (p.S4814A) ( ENST00000333891.14, ENST00000423517.6, ENST00000618073.1 )
PCLO p.Ser4814Ala (p.S4814A) ( ENST00000333891.14, ENST00000423517.6, ENST00000618073.1 )
Associated Disease
Unipolar Depression
Source Database
DisGeNET
Description
A genome-wide association study implicated the polymorphism rs2522833 in the piccolo (PCLO) gene--involved in monoaminergic neurotransmission--as a risk factor for MDD.
Pubmed
22832909
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00244297684872273
Year of publication
2012
Drugs